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Peptides

IGF-1 LR3

IGF-1 LR3 is a modified insulin-like growth factor-1 analogue designed for in vitro research on cell growth, protein synthesis, and metabolic signalling. Its structural changes reduce binding to IGF-binding proteins, allowing for prolonged activity in experimental systems.

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1mg£69.99Out of Stock Get Notified

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IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1)

IGF-1 LR3 is a high-purity research peptide derived from human insulin-like growth factor-1 (IGF-1). It is widely used in advanced laboratory studies to investigate growth-factor signalling, protein synthesis, and metabolic pathways in controlled in vitro environments.

Key Features

Engineered to reduce IGF-binding protein (IGFBP) interaction for improved experimental consistency
Extended in vitro activity compared to native IGF-1
Lyophilised powder format for enhanced stability and storage
1 mg per vial for legitimate research applications
Produced under strict quality-controlled manufacturing processes

Product Overview

The Long R3 analogue incorporates a 13-amino-acid N-terminal extension and an arginine substitution at position 3. These structural modifications significantly reduce binding to IGFBPs, supporting increased availability and prolonged receptor interaction in experimental models. For laboratory research use only. Not for human or veterinary use.

Specifications

Product Name	IGF-1 LR3
Synonyms	Long R3 IGF-1; Long Arg3 IGF-1
Molecular Formula	C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
Molecular Weight	9,117.6 g/mol
CAS Number	946870-92-4
Form	Lyophilised powder
Appearance	White to off-white solid

Handling & Storage

Dry StorageStore in a cool, dry place away from light and moisture

ReconstitutionAllow vial and diluent to reach room temperature. Reconstitute with 10 ml bacteriostatic water. Gently swirl — do not shake or vortex

After ReconstitutionStore at 2–8 °C, protect from light, aliquot where possible, and avoid repeated temperature fluctuations

UsageFollow all institutional SOPs and applicable regulations

Research Applications

IGF-1 LR3 maintains strong affinity for the IGF-1 receptor while reducing interaction with IGFBPs, allowing for sustained signalling in vitro. Common research applications include:

Cell growth and differentiation studies
Protein synthesis and anabolic pathway analysis
Glucose metabolism and insulin signalling research

Complementary Products

Bacteriostatic Water 10 ml

Synthesis & Quality Assurance

Manufactured using validated solid-phase peptide synthesis (SPPS) techniques to ensure high purity and consistency. Each batch undergoes rigorous testing for identity, purity, and visual quality prior to release.

Legal & Safety Notice

All RXSRCHchem products are intended strictly for laboratory research purposes. They are not approved for use as pharmaceuticals, food, dietary supplements, or cosmetics, and are not for human or animal use. By purchasing, you confirm that you are qualified to handle research materials and will comply with all applicable laws and institutional guidelines.